Marlborough was named after the market town of Marlborough, England. The Calgary neighbourhood was established in 1967. It is bordered by the Trans-Canada Highway to the north, Memorial Drive to the south, 52 Street NE to the east, and 36 Street NE to the west.
Before its establishment, Marlborough was largely undeveloped. There was a large open field utilized for industrial storage. A small motel seemed to be the only major establishment then. By the 1970s, a cloverleaf interchange was created in the area to improve accessibility. That started the major development in Marlborough, which eventually became a residential neighbourhood.
Now, major establishments are just a few minutes away. The Marlborough Mall, which has a Wal-Mart as anchor store, is the neighbourhood's largest shopping destination.